Testosterone (Adult Females, Children, or Individuals on Testosterone-Suppressing Hormone Therapy)
Ordering Recommendation
Use this mass spectrometry test to measure a wide range of testosterone concentrations. Most useful when low concentrations are expected, regardless of the patient’s sex assigned at birth. Use to monitor testosterone-suppressing hormone therapies (eg, antiandrogens or estrogens). Free or bioavailable testosterone measurements may provide supportive information.
To compare this test to other testosterone tests, refer to the ARUP Testosterone Tests Comparison table.
New York DOH Approval Status
Specimen Required
Collect between 6-10 a.m.
Serum separator tube or green (sodium or lithium heparin).
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP standard transport tube. (Min: 0.2 mL)
Refrigerated.
EDTA plasma.
After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 6 months
Methodology
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun-Sat
Reported
1-5 days
Reference Interval
Effective August 19, 2013
Age |
Female |
Male |
---|---|---|
Premature (26-28 weeks) | 5-16 ng/dL | 59-125 ng/dL |
Premature (31-35 weeks) | 5-22 ng/dL | 37-198 ng/dL |
Newborn | 20-64 ng/dL | 75-400 ng/dL |
1-5 months | Less than 20 ng/dL | 14-363 ng/dL |
6-24 months | Less than 9 ng/dL | Less than 37 ng/dL |
2-3 years | Less than 20 ng/dL | Less than 15 ng/dL |
4-5 years | Less than 30 ng/dL | Less than 19 ng/dL |
6-7 years | Less than 7 ng/dL | Less than 13 ng/dL |
8-9 years | 1-11ng/dL | 2-8 ng/dL |
10-11 years | 3-32 ng/dL | 2-165 ng/dL |
12-13 years | 6-50 ng/dL | 3-619 ng/dL |
14-15 years | 6-52 ng/dL | 31-733 ng/dL |
16-17 years | 9-58 ng/dL | 158-826 ng/dL |
18-39 years | 9-55 ng/dL | 300-1080 ng/dL |
40-59 years | 9-55 ng/dL | 300-890 ng/dL |
60 years and older | 5-32 ng/dL | 300-720 ng/dL |
Premenopausal (18 years and older) | 9-55 ng/dL | Does Not Apply |
Postmenopausal | 5-32 ng/dL | Does Not Apply |
Tanner Stage I | 2-17 ng/dL | 2-15 ng/dL |
Tanner Stage II | 5-40 ng/dL | 3-303 ng/dL |
Tanner Stage III | 10-63 ng/dL | 10-851 ng/dL |
Tanner Stage IV-V | 11-62 ng/dL | 162-847 ng/dL |
Interpretive Data
Free or bioavailable testosterone measurements may provide supportive information.
For individuals on testosterone-suppressing hormone therapies (e.g., antiandrogens or estrogens), refer to cisgender female reference intervals. For a complete set of all established reference intervals, refer to ltd.aruplab.com/Tests/Pub/0081058.
Laboratory Developed Test (LDT)
Note
Hotline History
Hotline History
CPT Codes
84403
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0081058 | Testosterone by Mass Spec | 2986-8 |
Aliases
- Total Testosterone